06/14/2019 / By Evangelyn Rodriguez
Researchers from Guangzhou University of Chinese Medicine in China isolated and identified small-molecule STAT3 signaling inhibitors from the root extracts of the Japanese knotweed (Polygonum cuspidatum). Their results, which included the evaluation of in vitro anticancer activities of these STAT3 signaling inhibitors, were published in the journal BMC Complementary and Alternative Medicine.
Based on these findings, the researchers concluded that 2-ethoxystypandrone is a potent STAT3 signaling inhibitor capable of inhibiting the proliferation of HCC cells and HCC CSCs, which makes it a promising anti-CSC agent.
Read the full study at this link.
Journal Reference:
Li W, Zhang Q, Chen K, Sima Z, Liu J, Yu Q, Liu J. 2-ETHOXYSTYPANDRONE, A NOVEL SMALL-MOLECULE STAT3 SIGNALING INHIBITOR FROM POLYGONUM CUSPIDATUM, INHIBITS CELL GROWTH AND INDUCES APOPTOSIS OF HCC CELLS AND HCC CANCER STEM CELLS. BMC Complementary and Alternative Medicine. February 2019;19(1). DOI: 10.1186/s12906-019-2440-9
Tagged Under: 2-ethoxystypandrone, alternative medicine, anticancer, apoptosis, cancer cures, cancer treatment, disease treatments, hepatocellular carcinoma, herbal medicine, Herbs, Japanese knotweed, liver health, longevity, natural cures, natural medicine, Polygonum cuspidatum, remedies, research, TCM, traditional Chinese medicine
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