05/08/2019 / By Evangelyn Rodriguez
In this study, researchers from Shuguang Hospital in China investigated the mechanisms underlying the ability of gypenosides (GPs) – the predominant component of Gynostemma pentaphyllum or poor man’s ginseng – to ameliorate liver fibrosis. The results of their study were published in The American Journal of Chinese Medicine.
These results demonstrated that GPs can ameliorate CCl4-induced liver fibrosis by inhibiting TGF-B signaling, consequently inhibiting the differentiation of HPCs into myofibroblasts.
Journal Reference:
Chen J, Li X, Hu Y, Liu W, Zhou Q, Zhang H, Mu Y, Liu P. GYPENOSIDES AMELIORATE CARBON TETRACHLORIDE-INDUCED LIVER FIBROSIS BY INHIBITING THE DIFFERENTIATION OF HEPATIC PROGENITOR CELLS INTO MYOFIBROBLASTS. The American Journal of Chinese Medicine. 2017;45(05):1061–1074. DOI: 10.1142/s0192415x17500574
Tagged Under: alternative medicine, antifibrotic effects, disease treatments, Gynostemma pentaphyllum, gypenosides, herbal medicine, Herbs, liver damage, liver fibrosis, liver health, natural cures, natural medicine, poor man's ginseng, prevention, remedies, research