04/22/2019 / By Janine Acero
Researchers at the Sun Yat-sen University in Guangzhou, China evaluated the neuroactive effects of the ethanol extract of Schisandra chinensis and its components schisandrin and schisandrin B, and determined the underlying mechanisms using zebrafish behavioral profiling. Their findings were published in the Chinese Journal of Natural Medicines.
In conclusion, the main lignin components of S. chinensis exhibited neuroactive effects in zebrafish as shown through behavioral profiling. The researchers also concluded that this method can be used to predict the molecular pathways of TCM extracts and their components.
Journal Reference:
Wang JW, Liang FY, Ouyang XS, Li PB, Pei Z, Su WW. EVALUATION OF NEUROACTIVE EFFECTS OF ETHANOL EXTRACT OF SCHISANDRA CHINENSIS, SCHISANDRIN, AND SCHISANDRIN B AND DETERMINATION OF UNDERLYING MECHANISMS BY ZEBRAFISH BEHAVIORAL PROFILING. Chinese Journal of Natural Medicines. December 2018;16(12):916–925. DOI: 10.1016/s1875-5364(18)30133-x
Tagged Under: alternative medicine, behavior profiling, brain function, dopamine pathway, five-flavor berry, functional food, insomnia, neuroactive effects, remedies, Schisandra chinensis, serotonin pathway, sleep, sleep disorders, traditional Chinese medicine, zebrafish