Wooly bluecurls holds potential as natural cure for rheumatism

Wooly bluecurls (Trichostema lanatum Benth.) is traditionally used as a disinfectant and treatment for rheumatism by the Chumash people of Southern California. However, there were no scientific investigations to back up these applications of the plant. In this study, published in Medicines, researchers evaluated the antibacterial and immunomodulatory activities of extracts from the leaves of wooly bluecurls.

• Rheumatism is a health condition that is linked to excessive inflammation and other macrophage-mediated immune responses.
• Natural remedies for inflammation often work by regulating pro-inflammatory chemicals that can cause sepsis, tissue damage, and chronic inflammation when produced in excess.
• Antibacterial activity of wooly bluecurls extracts was determined against six Gram-positive and two Gram-negative bacteria.
• The researchers used murine macrophage cell cultures to assess the immunomodulatory activity of the extracts. They used the amount of tumor necrosis factor-alpha (TNF-alpha) produced as the basis for their evaluation.

From the results of the study, the researchers concluded that wooly bluecurls is an effective disinfectant since it was able to inhibit the growth of Gram-positive bacteria. However, it was not effective against Gram-negative bacteria that have the ability to pump treatments out of the cell. The results also prove that wooly bluecurls is an effective treatment for rheumatism since it can regulate inflammation by inhibiting macrophage proliferation and TNF-alpha production.

Read the full text of the study at this link.

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Journal Reference:

Fleming MC, Hester V, Allison BJ, Foster MC, Nofziger D, Joyner PM. IMMUNOMODULATORY AND ANTIBACTERIAL PROPERTIES OF THE CHUMASH MEDICINAL PLANT TRICHOSTEMA LANATUM. Medicines. 21 March 2018;5(2). DOI: 10.3390/medicines5020025